Acetyl Hexapeptide-8 is a peptide composed of six amino acids, with the chemical formula C₃₄H₆₀N₁₄O₁₂S and a molecular weight of approximately 888.9. It is a white crystalline powder, soluble in water and glycerol, and is most stable at pH 5 .
Its main function is anti - wrinkle. It works by competing with SNAP - 25 for binding sites, interfering with the formation of the SNARE complex, thus blocking the release of acetylcholine, weakening muscle contraction, and reducing the appearance of dynamic and expression lines. In addition, it can stimulate the skin's own collagen production, increase skin thickness and elasticity, and has antioxidant properties, which can scavenge free radicals. It also helps to enhance the skin's moisture - retaining ability, making the skin smoother, more delicate and shiny.
Acetyl Hexapeptide-8 is widely used in anti - wrinkle and firming skin care products, such as serums, creams, and eye creams. It is often used in combination with other anti - aging ingredients, such as sodium hyaluronate, niacinamide, etc., to achieve better anti - aging effects. According to relevant regulations, the safe use concentration of Acetyl Hexapeptide-8 in leave - on cosmetics is no higher than 0.005%, and in rinse - off cosmetics is no higher than 0.000005.
| Property |
Details |
| CAS Number |
616204 - 22 - 9 |
| Chemical Formula |
C₃₄H₆₀N₁₄O₁₂S |
| Molecular Weight |
About 888.99 |
| Amino Acid Sequence |
Ac - Glu - Glu - Met - Gln - Arg - Arg - NH2 |
| Appearance |
White to off - white powder |
| Solubility |
Soluble in water, glycerol |
| Optimal pH |
5 - 7 |
| Recommended Addition Amount |
50 - 500ppm6 |
